AN INVESTMENT IN YOUR HEALTH NOW AND FOR THE FUTURE

Learn more about which medications are most likely to work for you. Covering some of the most commonly prescribed medications.

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WHAT IS A MYDNA MEDICATION TEST?

A myDNA medication test is a PGx test that helps identify which medications are likely to be most suited to an individual. The test results are presented in a report for the healthcare professional to consider when deciding on the choice of medication for their patient.

WHAT IS PHARMACOGENOMICS (PGX)?

PGx is the study of how genetic factors influence the way a person responds to medications. PGx combines the study of pharmacology (study of how drugs work in the body) and genomics (study of genes and their functions). PGx is now being used to help doctors select safe and effective medications for their patients based on their unique genetic makeup.

There are certain genes which contain instructions to build proteins called enzymes. These enzymes are involved in breaking down many medications in the body, primarily in the liver. People have different versions of these genes which produce enzymes with varying levels of activity (e.g. slow, normal or fast). As a result, people can vary in how slow or fast they break down and clear medications from their body, and this can influence how well a medicine works or the risk of side effects for that individual.

Although not all medications are processed by these enzymes, a myDNA PGx test can provide information on a range of commonly prescribed medications, and indicate to your doctor whether there is anything additional they should be aware of if prescribing them. If you wish to clarify which medications are covered by each test, discuss this with your local myDNA provider prior to having your test.

Please note that we’ll deliver your report directly to your nominated healthcare professional. You will have ongoing access to your report after you have had a consultation with your doctor or pharmacist.

What you can learn in this report

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MENTAL HEALTH

Learn how your body responds to certain medications prescribed for mental health (includes antidepressants, antipsychotics, ADHD medications and anti-anxiety medications)

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PAIN

Learn how your body responds to certain medications prescribed for pain (includes opioids and NSAIDs)

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CARDIOVASCULAR

Learn how your body responds to certain medications prescribed for the cardiovascular system (includes cholesterol-lowering agents, blood thinners and beta blockers

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GASTROINTESTINAL

Learn how your body responds to certain medications prescribed for acid reflux and nausea

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GENES & MEDICATION

Discover what your genetic make up means for how your body processes certain medications

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LIFETIME RELEVANCE

Your genes remain the same your entire life, and your results can be used to optimise both current and future prescribing considerations

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RECOMMENDATIONS

Prescribing recommendations for your doctor, based on your individual results. Completed reports are delivered to your doctor or pharmacist so that they can review the results before providing you with a copy

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OUR AUSTRALIAN LAB ANALYSIS

All cheek swab samples are analysed in an Australian laboratory. Our National Association of Testing Authorities (NATA) accredited laboratory located in Melbourne, Australia.

myDNA Life is also an Organisational Member of the Global Alliance for Genomics and Health.

Under lock and key

myDNA will interpret and provide a personalised report for the genetic myDNA test requested by you or your healthcare professional only. Your reports and genetic data are your property. Any results generated remain strictly confidential and will not be shared with any third parties without your consent. Privacy and data security protocols are fundamental to the myDNA technology platform.

Test limitations

The myDNA medication test detects common variants in 9 genes (6 genes encoding CYP450 drug metabolising enzymes, VKORC1, encoding a protein that partially determines sensitivity to warfarin, OPRM1, encoding the mu receptor which has been associated with opioid sensitivity, and SLCO1B1, encoding a drug transporter important for statins). The genes tested in the myDNA medication test have clinically significant associations which have been documented in the peer-reviewed literature and, for some have associated published clinical practice guidelines.

There are important myDNA test limitations to consider:

  • The test only provides information about medications for which one or more of the nine genes are known to influence medication concentration or response. Therefore, the test cannot determine how individuals respond to all medications in clinical use.
  • Response to medications is complex and often incompletely understood. The myDNA medication test only looks at one aspect which may affect medication response (i.e. changes in drug concentration due to genetic variation) and this should be considered when interpreting the test. Of note, a “normal” result does not predict that the patient will always respond to a medication and not experience any side effects, and allergic reactions cannot be detected by this genetic test.
  • The test does not detect all known variants in the genes tested. Only common variants are tested that are present in Caucasian, African and Asian backgrounds. If an individual carries a rare variant or a variant mostly found in other ethnicities, then this variant will not be detected, the allele will be classified as the default or wild type (e.g. *1) and the phenotype may be inaccurate. Only testing the common variants is the practice of most screening molecular genetic testing laboratories around the world.

*Note all reports and online portal information will be in English