MEDICATION – Static
AN INVESTMENT IN YOUR HEALTH NOW AND FOR THE FUTURE
Learn more about which medications are most likely to work for you. Covering some of the most commonly prescribed medications.
MEDICATION – What is DNA
What is DNA?
DNA folds into paired packages called chromosomes. Chromosomes contain many genes. A gene is a section of DNA that holds the instructions to build a protein. People can have different versions of the same gene. Our bodies are made of around 24,000 genes, using around 3% of our DNA.
DNA is the blueprint for life. Think of DNA as an assembly manual that is used to build each and every one of us.
Proteins are essential for life and perform a huge variety of jobs, from controlling the function of a single cell, to determining the shape of our bodies.
We share very similar DNA with one another, 99% in fact. But it’s the 1% that makes us individuals, giving us different e.g. facial features, hair colour, height, etc…
MEDICATION – Meds test
WHAT IS A MYDNA MEDICATION TEST?
A myDNA medication test is a PGx test that helps identify which medications are likely to be most suited to an individual. The test results are presented in a report for the healthcare professional to consider when deciding on the choice of medication for their patient.
WHAT IS PHARMACOGENOMICS (PGX)?
PGx is the study of how genetic factors influence the way a person responds to medications. PGx combines the study of pharmacology (study of how drugs work in the body) and genomics (study of genes and their functions). PGx is now being used to help doctors select safe and effective medications for their patients based on their unique genetic makeup.
There are certain genes which contain instructions to build proteins called enzymes. These enzymes are involved in breaking down many medications in the body, primarily in the liver. People have different versions of these genes which produce enzymes with varying levels of activity (e.g. slow, normal or fast). As a result, people can vary in how slow or fast they break down and clear medications from their body, and this can influence how well a medicine works or the risk of side effects for that individual.
Although not all medications are processed by these enzymes, a myDNA PGx test can provide information on a range of commonly prescribed medications, and indicate to your doctor whether there is anything additional they should be aware of if prescribing them. If you wish to clarify which medications are covered by each test, discuss this with your local myDNA provider prior to having your test.BOOK YOUR CONSULT
Please note that we’ll deliver your report directly to your nominated healthcare professional. You will have ongoing access to your report after you have had a consultation with your doctor or pharmacist.
MEDICATION – Report benefits
MEDICATION – What it gives you
GENES & MEDICATION
Discover what your genetic makeup means for how your body processes certain medications
Prescribing recommendations for your doctor so that they can review and discuss the results with you before providing you with a copy.
Your genes remain the same your entire life, and your results can be used to optimise both current and future prescribing considerations
Learn how your body responds to certain medications prescribed for mental health (includes antidepressants, antipsychotics, ADHD medications and anti-anxiety medications)
Learn how your body responds to certain medications prescribed for pain (includes opioids and NSAIDs)
Learn how your body responds to certain medications prescribed for the cardiovascular system (includes cholesterol-lowering agents, blood thinners and beta blockers)
Learn how your body responds to certain medications prescribed for acid reflux and nausea
MEDICATION – Stories
Rachel shares her story
Joy shares her story
MEDICATIONS – NATA
OUR AUSTRALIAN LAB ANALYSIS
All cheek swab samples are analysed in an Australian laboratory. Our National Association of Testing Authorities (NATA) accredited laboratory located in Melbourne, Australia.
myDNA Life is also an Organisational Member of the Global Alliance for Genomics and Health.
NUTRITION – Lock and key
Under Lock and Key
myDNA will interpret and provide a personalised report for the genetic myDNA test requested by you. Your reports and genetic data are your property. Any results generated remain strictly confidential and will not be shared with any third parties without your consent. Privacy and data security protocols are fundamental to the myDNA technology platform.
MEDICATION – Limitations
The myDNA medication test detects common variants in 9 genes (6 genes encoding CYP450 drug metabolising enzymes, VKORC1, encoding a protein that partially determines sensitivity to warfarin, OPRM1, encoding the mu receptor which has been associated with opioid sensitivity, and SLCO1B1, encoding a drug transporter important for statins). The genes tested in the myDNA medication test have clinically significant associations which have been documented in the peer-reviewed literature and, for some have associated published clinical practice guidelines.
There are important myDNA test limitations to consider:
- The test only provides information about medications for which one or more of the nine genes are known to influence medication concentration or response. Therefore, the test cannot determine how individuals respond to all medications in clinical use.
- Response to medications is complex and often incompletely understood. The myDNA medication test only looks at one aspect which may affect medication response (i.e. changes in drug concentration due to genetic variation) and this should be considered when interpreting the test. Of note, a “normal” result does not predict that the patient will always respond to a medication and not experience any side effects, and allergic reactions cannot be detected by this genetic test.
- The test does not detect all known variants in the genes tested. Only common variants are tested that are present in Caucasian, African and Asian backgrounds. If an individual carries a rare variant or a variant mostly found in other ethnicities, then this variant will not be detected, the allele will be classified as the default or wild type (e.g. *1) and the phenotype may be inaccurate. Only testing the common variants is the practice of most screening molecular genetic testing laboratories around the world.
GENERAL – Reports in English
*Note all reports and online portal information will be in English