{"id":106614,"date":"2020-07-09T06:22:49","date_gmt":"2020-07-08T18:22:49","guid":{"rendered":"https:\/\/www.mydna.life\/en-nz\/?page_id=106614"},"modified":"2025-05-20T12:26:27","modified_gmt":"2025-05-20T00:26:27","slug":"healthcare-professionals","status":"publish","type":"page","link":"https:\/\/www.mydna.life\/en-nz\/healthcare-professionals\/","title":{"rendered":"Healthcare Professionals"},"content":{"rendered":"

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What is Pharmacogenomics?<\/span><\/h3>\n

Pharmacogenomics (PGx) is the study of how genetic variations influence the way an individual responds to medications.<\/span><\/p>\n

PGx is now enabling doctors to test for specific genetic changes to predict whether a patient may have a normal response, a poor response, or a higher risk of side effects before prescribing a specific medication.<\/span><\/p>\n

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Clinical Support
\nPharmacogenomic Testing<\/span><\/h3>\n

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O<\/span>ur clinical team is here to support you and answer all your questions on either individual results or how to best interpret the report.<\/span><\/p>\n

Our dedicated pharmacogenomics specialist team includes clinical geneticists, clinical pharmacologists, molecular geneticists and pharmacists.<\/span><\/p>\n

Simply call us on 1300 436 373 or email us on help@mydna.life<\/a>.<\/strong><\/p>\n

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Printable Resources<\/span><\/h3>\n

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To support the conversation with your patient we have a Doctor’s Overview<\/strong>, Patient Information<\/strong> and a Substrate Card<\/strong> covering all the medications that we provide results for. These documents can be used for your reference.<\/p>\n

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Doctor’s Overview<\/h5>\n

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Patient Education<\/h5>\n

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Substrate Card<\/h5>\n

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Please contact our customer service team for access to our training resources.<\/p>\n

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Pharmacogenomics has Long Term <\/span>Healthcare Benefits<\/h3>\n

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Reduce the risk of adverse drug reactions<\/span><\/h6>\n

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Reduce trial-and-error when prescribing<\/span><\/h6>\n

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Offer a personalised<\/span> healthcare service<\/strong><\/h6>\n

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Results have a lifetime relevance<\/span><\/strong><\/h6>\n

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Reduce wasted cost<\/span> on ineffective medication<\/strong><\/h6>\n

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Fast-track<\/span> treatment goals<\/strong><\/h6>\n

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What do we offer?<\/span><\/h3>\n

[\/vc_column_text][vc_column_text css_animation=”fadeIn”]The myDNA Medication tests use PGx to identify variations in a number of genes that influence responses to medications and healthcare treatments.<\/p>\n

We concentrate on the genes encoding the metabolising enzymes (i.e. CYP450 enzymes) which are found mainly in the liver and the gut wall. These genetic variations predict the level of enzyme activity which in turn results in increased or decreased plasma concentrations and drug exposure.<\/p>\n

Increased plasma concentrations, due to reduced enzyme activity, can lead to adverse effects. Reduced plasma concentrations, due to increased enzyme activity, can lead to poor therapeutic response.<\/p>\n

We offer a\u00a0multiple medications test, which covers multiple medication categories (currently in excess of over 80 medications). However, if a specific category is more suitable, we also offer\u00a0single category medication reports.[\/vc_column_text][\/vc_column][vc_column width=”1\/2″][vc_row_inner equal_height=”yes” content_placement=”top”][vc_column_inner width=”1\/2″ offset=”vc_col-xs-6″ css=”.vc_custom_1594343142052{padding-bottom: 2rem !important;}”][vc_single_image image=”120160″ img_size=”115×115″ alignment=”center”][vc_column_text css_animation=”fadeIn”]<\/p>\n

Mental Health<\/h6>\n

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Pain<\/h6>\n

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Oncology<\/h6>\n

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Gastrointestinal<\/h6>\n

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Cardiovascular<\/h6>\n

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Reduce trial-and-error<\/span><\/h3>\n

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Likelihood<\/h6>\n

of experiencing side effects if taking 5+ medications1<\/sup>.<\/p>\n

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Of<\/span> patients<\/h6>\n

with depression don\u2019t have complete remission of their illness when initially treated with antidepressants2<\/sup>.<\/p>\n

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1 in 10<\/span> people<\/h6>\n

May process certain medications too slowly, increasing their risk of side effects3<\/sup>.<\/p>\n

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1 in 3<\/span> people<\/h6>\n

May process certain medications too quickly, increasing their risk of treatment failure3<\/sup>.<\/p>\n

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Patients most likely to benefit<\/span> from our insights:<\/h5>\n

<\/i> Those experiencing side effects to specific medications<\/strong><\/span><\/p>\n

<\/i> Anyone not responding to specific medications<\/strong><\/span><\/p>\n

<\/i> Patients requiring doses of medications outside the recommended range<\/strong><\/span><\/p>\n

<\/i> Patients planning to start on a new medication covered by the myDNA test<\/strong><\/span><\/p>\n

<\/i> Anyone taking multiple medications<\/strong><\/span>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/5″][\/vc_column_inner][\/vc_row_inner][vc_column_text]<\/p>\n

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  1. Bourgeois FT, Shannon MW, Valim C, et al. Adverse drug events in the outpatient setting: an 11-year national analysis. Pharmacoepidemiol Drug Saf. 2010;19:901\u201310<\/li>\n
  2. Rush AJ, Trivedi MH, Wisniewski SR, Stewart JW, Nierenberg AA, Thase ME et al. Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression. NEnglJ Med 2006; 354: 1231\u20131242<\/li>\n
  3. Hicks JK, Sangkuhl K, Swen JJ, Ellingrod VL, Muller DJ, Shimoda K, et al. Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update. Clin Pharmacol Ther. 2017;102(1):37-44.<\/li>\n<\/ol>\n

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    PGx Healthcare in practice<\/span><\/h3>\n

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    Customer success<\/span> stories<\/h3>\n

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    PGx is in our DNA<\/span><\/h3>\n

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    Associate Professor Les Sheffield<\/strong><\/h4>\n

    Clinical Geneticist & myDNA Co-Founder<\/strong>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″ offset=”vc_col-xs-12″][vc_column_text css_animation=”fadeIn”]Since the 1980s Professor Sheffield has been involved in the design and development of genetic tests. As a Clinical Geneticist, he has authored more than 100 scientific publications. In 2007 he founded myDNA to assist in more informed prescribing of medications. He continues to drive the development of new healthcare services as Medical Director.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_btn title=”Meet Our Team” align=”center” i_icon_fontawesome=”fa fa-flask” add_icon=”true” link=”url:https%3A%2F%2Fwww.mydna.life%2Fen-nz%2Four-experts%2F|title:Our%20Experts||” el_class=”primary-button”][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1659923406887{padding-bottom: 30px !important;background-color: #f4f4f4 !important;}”][vc_column][vc_column_text]It is estimated that the Australian healthcare system would save over $1 billion per year by implementing pharmacogenetic testing and thereby avoiding many adverse drug reactions.1<\/sup> Further substantial savings would accrue from avoiding wastage of drugs that were predicted to be ineffective for a patient, and from improved health outcomes for patients.2<\/sup>[\/vc_column_text][vc_column_text]<\/p>\n

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    1. Australian Centre for Health Research. Improving the Quality Use of Medicines in Australia. [Internet] 2008 [cited 2022 July 28]; Available from: https:\/\/globalaccesspartners.org\/Improving_the_Quality_Use_of_Medicines_in_Australia.pdf<\/li>\n
    2. The Royal College of Pathologies of Australia. Utilisation of pharmacogenetics in healthcare. [Internet] 2018 [cited 2022 July 28]; Available from: https:\/\/www.rcpa.edu.au\/Library\/College-Policies\/Position-Statements\/Utilisation-of-pharmacogenetics-in-healthcare<\/li>\n<\/ol>\n

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      Evidence<\/span> behind pharmacogenomic testing<\/h3>\n

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      We reference the guidelines of the Royal Dutch Pharmacists Association, Pharmacogenetics Pharmacogenomics Working Group<\/a>\u00a0& the\u00a0Clinical Pharmacogenetics Implementation Consortium (CPIC)<\/a>, which have been most recently published.<\/p>\n

      The following publications contain significant evidence for gene-drug associations of which dosage adjustments have been recommended.<\/p>\n

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      1. CPIC Guideline for CYP2D6 and CYP2C19 genotypes and dosing of Tricyclic Antidepressants<\/li>\n
      2. CPIC Guideline for CYP2D6 and CYP2C19 genotypes and dosing of Selective Serotonin Reuptake Inhibitors (SSRIs)<\/li>\n
      3. Dutch Pharmacogenetics Working Group guidelines which include a number of antidepressant and antipsychotic medications<\/li>\n<\/ol>\n

        [\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_btn title=”Our Full List of References” align=”center” i_icon_fontawesome=”far fa-newspaper” css=”.vc_custom_1604021786228{margin-top: 5vh !important;}” add_icon=”true” el_class=”primary-button” link=”url:https%3A%2F%2Fwww.mydna.life%2Fen-nz%2Fclinical-references%2F|title:Read%20our%20Full%20List%20of%20Scientific%20References”][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1594353923492{padding-top: 10vh !important;padding-bottom: 10vh !important;}”][vc_column width=”1\/5″][\/vc_column][vc_column width=”3\/5″][vc_column_text css_animation=”none” css=”.vc_custom_1594357730531{padding-bottom: 1em !important;}”]<\/p>\n

        Our scientific<\/span> partner network<\/h3>\n

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        A growing global network<\/span> with the flexibility to scale and customise accordingly<\/h3>\n

        [\/vc_column_text][vc_column_text]<\/p>\n

        AUSTRALIA | NEW ZEALAND | USA | CANADA | UK | INDONESIA | SINGAPORE | THAILAND | PHILIPPINES | VIETNAM | BANGLADESH<\/strong><\/h4>\n

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        Trusted accreditation<\/span> on a global scale<\/h3>\n

        [\/vc_column_text][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1594356869263{padding-bottom: 10vh !important;}”][vc_column width=”1\/6″][\/vc_column][vc_column width=”2\/3″][vc_row_inner content_placement=”top”][vc_column_inner width=”1\/6″ offset=”vc_col-xs-4″][vc_single_image image=”106661″ img_size=”full” alignment=”center” onclick=”custom_link” css_animation=”fadeIn” link=”https:\/\/www.nata.com.au\/”][\/vc_column_inner][vc_column_inner width=”1\/6″ offset=”vc_col-xs-4″][vc_single_image image=”106663″ img_size=”full” alignment=”center” onclick=”custom_link” css_animation=”fadeIn” link=”https:\/\/www.tga.gov.au\/”][\/vc_column_inner][vc_column_inner width=”1\/6″ offset=”vc_col-xs-4″][vc_single_image image=”106664″ img_size=”full” alignment=”center” onclick=”custom_link” css_animation=”fadeIn” link=”http:\/\/https:\/\/www.fda.gov\/home”][\/vc_column_inner][vc_column_inner width=”1\/6″ offset=”vc_col-xs-4″][vc_single_image image=”106666″ img_size=”full” alignment=”center” onclick=”custom_link” css_animation=”fadeIn” link=”https:\/\/www.canada.ca\/en\/health-canada.html”][\/vc_column_inner][vc_column_inner width=”1\/6″ offset=”vc_col-xs-4″][vc_single_image image=”106668″ img_size=”full” alignment=”center” onclick=”custom_link” css_animation=”fadeIn” link=”https:\/\/www.medsafe.govt.nz\/”][\/vc_column_inner][vc_column_inner width=”1\/6″ offset=”vc_col-xs-4″][vc_single_image image=”106662″ img_size=”full” alignment=”center” onclick=”custom_link” css_animation=”fadeIn” link=”https:\/\/www.ga4gh.org\/”][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=”1\/6″][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1659924015459{padding-top: 10vh !important;padding-bottom: 10vh !important;background-color: #efefef !important;}”][vc_column][vc_column_text css=”.vc_custom_1659924044757{padding-bottom: 2rem !important;}”]<\/p>\n

        Your data<\/span> under lock and key<\/h3>\n

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        Your DNA sample and data remain your property, are stored on secure encrypted services, can be destroyed anytime at your request, and will never be shared without your consent.<\/p>\n

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        Our analysis is limited to the DNA markers we report on. Your results won\u2019t include diseases, can\u2019t be used to identify you, nor will they have any bearing towards insurance policies.<\/p>\n

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        Enquire<\/span> about genomic reporting for your business<\/h3>\n

        Leave your details below and our partnership team will be in touch.<\/strong><\/p>\n

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        <\/div>
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