Provide a unique professional service in pharmacy
By offering myDNA in your pharmacy, you can now provide a more personalised service to your customers.
About our test
The myDNA Medication tests use pharmacogenomics to identify variations in a number of genes that influence medication response.
Currently, myDNA Medication reports concentrate on the genes encoding the metabolising enzymes (i.e. CYP450 enzymes) which are found mainly in the liver as well as the gut wall. These genetic variations predict the level of enzyme activity which in turn results in increased or decreased plasma concentrations and drug exposure.
Increased plasma concentrations, due to reduced enzyme activity, can lead to adverse effects. Reduced plasma concentrations, due to increased enzyme activity, can lead to poor therapeutic response.
myDNA offers a multiple gene medication test, which covers multiple medication categories (currently in excess of 80 medications). If information on medications in a specific therapeutic area is of interest, myDNA offers four single category medication reports as shown below.
- Pain medication
- Mental health medications
- Cardiovascular medications
- Gastrointestinal medications.
Enzyme function can also be affected by factors other than genotype, including age, the effect of co-administered drugs (i.e. drug-drug interactions), and the presence of liver disease. These should be taken into account when considering the myDNA Medication Reports.
Reports must be delivered by a suitable healthcare professional. myDNA provides training for medical staff to assist in the understanding of these reports. If you would like to know more about this training, please email us: email@example.com.
WHAT IS A MYDNA MEDICATION TEST?
A myDNA medication test is a PGx test that helps identify which medications are likely to be most suited to an individual. The test results are presented in a report for the healthcare professional to consider when deciding on the choice of medication for their patient.
The patients likely to benefit from myDNA testing include those who are:
- Experiencing side effects to specific medications
- Not responding to specific medications
- Requiring doses of specific medications outside the recommended range
- Planning to start on a new medication covered by the myDNA test
- Taking multiple medications
Each person who takes a myDNA test will receive a highly customised medication report and ongoing access to their Explore myDNA – a secure online portal that provides information relevant to the person’s genetic profile.
Medication covered by the myDNA medication test
The myDNA Medication test examines the important DNA variants that affect drug response for over 80 medications used in clinical practice. These include certain antidepressants, antipsychotics, analgesics, anticoagulants, antiplatelets and proton pump inhibitors. Current TGA regulations prohibit the myDNA website from listing individual medications by name, but a list of the main medications that can be tested for is available for doctors and pharmacists. Please email us: firstname.lastname@example.org to request a copy of the myDNA Quick Reference Medication list.
EVIDENCE BEHIND PHARMACOGENOMIC TESTING
In our reports, myDNA references the guidelines of the Royal Dutch Pharmacists Association – Pharmacogenetics Pharmacogenomics Working Group and the Clinical Pharmacogenetics Implementation Consortium (CPIC). Generally, the emphasis is on CPIC guidelines, given their more recent publication.
The following published guidelines contain evidence for gene-drug associations for which dosage adjustments have been recommended. These can be accessed online at CPIC.
- CPIC Guideline for CYP2D6 and CYP2C19 genotypes and dosing of Tricyclic Antidepressants
- CPIC Guideline for CYP2D6 and CYP2C19 genotypes and dosing of Selective Serotonin Reuptake Inhibitors (SSRIs)
- Dutch Pharmacogenetics Working Group guidelines which include a number of antidepressant and antipsychotic medications
Pharmacogenomic testing in pharmacies
myDNA was the first to offer pharmacogenomic testing in Australian pharmacies in 2015. Today it is available in more than 1,000 pharmacies nationwide.
Participating pharmacies are at the forefront of personalised medicine and are able to provide an enhanced service to their customers.
The myDNA test allows pharmacists to
Provide treatment of outcomes
BUILD STRONGER RELATIONSHIPS
OFFER A PERSONALISED HEALTH SERVICE
PROVIDE A POINT OF DIFFERENCE
EXPAND THEIR HEALTH SERVICES
ENCOURAGE PROFESSIONAL DEVELOPMENT
Offering myDNA in your pharmacy
Offering the myDNA program in your pharmacy is simple. Each pharmacy’s program manager nominates staff members who undertake comprehensive myDNA training.
We have helpful support staff and a clinical team if you ever require any assistance along the way.