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PROVIDE A UNIQUE PROFESSIONAL SERVICE

By offering myDNA in your pharmacy, you can now provide a more personalised service to your customers.

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DOCTOR – About the myDNA test

About our test

The myDNA Medication tests use pharmacogenomics to identify variations in a number of genes that influence medication response.

Currently, myDNA Medication reports concentrate on the genes encoding the metabolising enzymes (i.e. CYP450 enzymes) which are found mainly in the liver as well as the gut wall. These genetic variations predict the level of enzyme activity which in turn results in increased or decreased plasma concentrations and drug exposure.

Increased plasma concentrations, due to reduced enzyme activity, can lead to adverse effects. Reduced plasma concentrations, due to increased enzyme activity, can lead to poor therapeutic response.

myDNA offers a multiple gene medication test, which covers multiple medication categories (currently in excess of 80 medications). If information on medications in a specific therapeutic area is of interest, myDNA offers four single category medication reports as shown below.

  1. Pain Medication
  2. Mental health medications
  3. Cardiovascular Medications
  4. Gastrointestinal medications.

Enzyme function can also be affected by factors other than genotype, including age, the effect of co-administered drugs (i.e. drug-drug interactions), and the presence of liver disease. These should be taken into account when considering the myDNA Medication Reports.

Reports must be delivered by a suitable healthcare professional. myDNA provides training for medical staff to assist in the understanding of these reports. If you would like to know more about this training, please email us: [email protected].

References Testing methods and limitations Clinical FAQs

DOCTOR – Pharmacogenomic

Hear from our Associate Professor Les Sheffield

DOCTOR – Who is it Recommended For

The patients likely to benefit from myDNA testing include those who are:

  • Experiencing side effects to specific medications
  • Not responding to specific medications
  • Requiring doses of specific medications outside the recommended range
  • Planning to start on a new medication covered by the myDNA test
  • Taking multiple medications

Each person who takes a myDNA test will receive a highly customised medication report and ongoing access to their Explore myDNA – a secure online portal that provides information relevant to the person’s genetic profile.

Learn more

DOCTOR – Evidence

EVIDENCE BEHIND PHARMACOGENOMIC TESTING

In our reports, myDNA references the guidelines of the Royal Dutch Pharmacists Association – Pharmacogenetics Pharmacogenomics Working Group and the Clinical Pharmacogenetics Implementation Consortium (CPIC). Generally, the emphasis is on CPIC guidelines, given their more recent publication.

The following published guidelines contain evidence for gene-drug associations for which dosage adjustments have been recommended. These can be accessed online at CPIC.

  1. CPIC Guideline for CYP2D6 and CYP2C19 genotypes and dosing of Tricyclic Antidepressants
  2. CPIC Guideline for CYP2D6 and CYP2C19 genotypes and dosing of Selective Serotonin Reuptake Inhibitors (SSRIs)
  3. Dutch Pharmacogenetics Working Group guidelines which include a number of antidepressant and antipsychotic medications

Rx HOME – Testing in Pharmacies

Pharmacogenomic testing in pharmacies

myDNA was the first to offer pharmacogenomic testing in Australian pharmacies in 2015. Today it is available in more than 1,000 pharmacies nationwide.

Participating pharmacies are at the forefront of personalised medicine and are able to provide an enhanced service to their customers.

Rx HOME – Treatment success

The myDNA test allows pharmacists to:

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Rx HOME – Benefits

PROVIDE TREATMENT OUTCOMES

BUILD STRONGER RELATIONSHIPS

OFFER A PERSONALISED
HEALTH SERVICE

 

PROVIDE A POINT OF DIFFERENCE

EXPAND THEIR
HEALTH SERVICES

ENCOURAGE PROFESSIONAL DEVELOPMENT

Rx HOME – Offering myDNA

Offering myDNA in your pharmacy

Offering the myDNA program in your pharmacy is simple. Each pharmacy’s program manager nominates staff members who undertake comprehensive myDNA training.

We have helpful support staff and a clinical team if you ever require any assistance along the way.

Rx HOME – Want to Learn More

WANT TO LEARN MORE?

Call us on 1300 436 373

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MEDS – Stories

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